Key result
Brachial-ankle pulse wave velocity (baPWV) tended to have a higher success rate for independent prognostic predictability compared to CAVI (65.7% vs 40.0%, p=0.083).
Why the study?
Does baPWV compared to CAVI have a higher success rate in independently predicting clinical prognosis?
Does baPWV compared to CAVI have a higher success rate in independently predicting clinical prognosis?
Large sample sizes and non-dialysis populations are key drivers for successfully validating arterial stiffness indices as prognostic markers, with baPWV showing a trend toward better predictive reliability than CAVI.
BACKGROUND: Brachial-ankle pulse wave velocity (baPWV) and cardio-ankle vascular index (CAVI) are indices of arterial stiffness, and several studies have used these indices. However, there is no comprehensive review of these parameters in the prognostic significance. METHODS: The aim of this study was to review the articles exploring the prognostic significance of these parameters. Articles demonstrating independent significance after multivariate analysis on the Cox proportional hazards model were defined as "successful." The success rate was compared using Fisher's exact test. In addition, multivariate logistic regression analysis was performed to explore the independent determinants of the success of prognostic prediction. RESULTS: =0.060) exhibited statistical tendency in the multivariate analysis. CONCLUSION: This study demonstrated that the number of study participants and dialysis population were the independent determinants of the success of prognostic prediction. This study also showed the importance of exclusion criteria of ASO when using these indices. In addition, a prospective large-scale study to confirm the superiority in the prognostic prediction of these indices is warranted.
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Dai Ato (2018) conducted a review in Arterial stiffness (prognostic prediction) (n=85). Brachial-ankle pulse wave velocity (baPWV) vs. Cardio-ankle vascular index (CAVI) was evaluated on Success rate of independent prognostic predictability after multivariate analysis (p=0.083). Brachial-ankle pulse wave velocity (baPWV) tended to have a higher success rate for independent prognostic predictability compared to CAVI (65.7% vs 40.0%, p=0.083).
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