Key result
Trier Social Stress Task increases brachial-femoral pulse wave velocity versus neutral control in young adults.
Why the study?
Acute psychological stress may contribute to cardiovascular disease risk through transient vascular dysfunction, addressing limitations identified in prior studies.
Does the Trier Social Stress Task increase brachial-femoral pulse wave velocity in healthy young adults?
RCT
Crossover
Does the Trier Social Stress Task increase brachial-femoral pulse wave velocity in healthy young adults?
Acute psychological stress transiently increases arterial stiffness, suggesting a mechanism linking repeated stress exposure to long-term cardiovascular risk.
Transient arterial stiffening from acute stress may add to cumulative CV risk; confirms and extends meta-analytic links via RCT evidence.
Acute psychological stress may contribute to cardiovascular disease risk through transient vascular dysfunction. In a randomized crossover study of healthy young adults, the Trier Social Stress Task increased brachial–femoral pulse wave velocity compared with a neutral time- and speech-matched control condition. Using an experimental design and statistical approach that addressed limitations identified in prior studies, these findings support meta-analytic evidence and suggest that transient arterial stiffening may represent a mechanism linking repeated stress exposure to long-term cardiovascular risk.
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Zieff et al. (2026) conducted an RCT in Healthy. Trier Social Stress Task vs. Neutral time- and speech-matched control condition was evaluated on brachial-femoral pulse wave velocity. The Trier Social Stress Task increased brachial-femoral pulse wave velocity compared with a neutral time- and speech-matched control condition in healthy young adults.
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