Why the study?
Does a linear, three-region, axially distributed model accurately estimate oxygen consumption from [15O]oxygen tracer data compared to experimental measurements in an isolated rabbit heart preparation?
Does a linear, three-region, axially distributed model accurately estimate oxygen consumption from [15O]oxygen tracer data compared to experimental measurements in an isolated rabbit heart preparation?
A novel mathematical model accurately estimates regional oxidative metabolism from [15O]oxygen tracer data, supporting its potential application in positron emission tomography (PET) imaging.
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Model matches experimental measures in isolated hearts; leaves open translation to in vivo PET oxygen consumption imaging.
Deußen et al. (1996) studied this question.
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