Treatment of Staphylococcal Septicemia With Sulfamethylthiazole and Sulfathiazole; A Report of Twelve Cases

Article1 January 1941TREATMENT OF STAPHYLOCOCCAL SEPTICEMIA WITH SULFAMETHYLTHIAZOLE AND SULFATHIAZOLE; A REPORT OF TWELVE CASESMORTON HAMBURGER, M.D., J. M. RUEGSEGGER, M.D.MORTON HAMBURGER, M.D.Search for more papers by this author, J. M. RUEGSEGGER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-7-1137 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe reported mortality from staphylococcal septicemia associated with foci of all sorts varies from 8 to 90 per cent.1-11Inspection of the summary of recent reports in table 1 shows that though reduction in the general mortality has followed the use of one or another therapeutic agent, the invasion of the blood stream by staphylococci is still a grave matter. Moreover, strict criteria for diagnosis are not always defined. Stookey and Scarpellino3insisted upon the presence of three positive blood cultures for inclusion of cases in their series, and excluded all cases of osteomyelitis, but most authors have not laid...Bibliography1. BAKERSHANDS LDAR: Staphylococcal osteomyelitis with staphylococcemia, Jr. Am. Med. Assoc., 1939, cxiii, 2119. Google Scholar2. DOLMAN CE: Staphylococcus antitoxic serum in the treatment of acute staphylococcal infections and toxemias, Canad. Med. Assoc. Jr., 1934, xxx, 601. Google Scholar3. STOOKEYSCARPELLINO PFLA: Staphylococcus septicemia, South. Med. Jr., 1939, xxxii, 172. Google Scholar4. JULIANELLE LA: Observations on the specific treatment (Type A antiserum) of staphylococcal septicemia, ANN. INT. MED., 1939, xiii, 308. Google Scholar5. MACNEALFRISBEE WJFC: Bacteriophage service to patients with staphylococcus septicemia, Am. Jr. Med. Sci., 1936, cxci, 170. CrossrefGoogle Scholar6. DUTTON LO: The therapeutic use of bacteriophage, with special reference to staphylococcus septicemia, Southwest. Med., 1933, xvii, 374. Google Scholar7. MACNEAL PS: Staphylococcus aureus septicemia; a preliminary report, Univ. Hosp. Bull., Ann Arbor, 1939, v, 58. Google Scholar8. GILBERT WM: Staphylococcus septicemia. Treatment with bacteriophage, Jr. Med. Assoc. Ga., 1938, xxvii, 155. Google Scholar9. MENDELL TH: Staphylococcic septicemia: a review of thirty-five cases, with six recoveries, twenty-nine deaths and sixteen autopsies, Arch. Int. Med., 1939, lxiii, 1068. CrossrefGoogle Scholar10. LOWENSTEIN PS: Staphylococcal septicemia, Am. Jr. Med. Sci., 1931, clxxxi, 196. CrossrefGoogle Scholar11. STOOKEYSCARPELLINOWEAVER PFLAJB: Immunology of osteomyelitis, Arch. Surg., 1936, xxxii, 494. CrossrefGoogle Scholar12. ROBERTSON DE: Acute hematogenous osteomyelitis, Jr. Bone and Joint Surg., 1938, xx, 35. Google Scholar13. MCKEERAKEGREEPVAN DYKE CMGROHB: Therapeutic effect of sulfathiazole and sulfapyridine, Proc. Soc. Exper. Biol. and Med., 1939, xlii, 417-421. CrossrefGoogle Scholar14. BRATTONMARSHALL ACEK: A new coupling component for sulfanilamide determination, Jr. Biol. Chem., 1939, cxxviii, 537. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cincinnati, Ohio*Received for publication August 9, 1940.From The Department of Internal Medicine, University of Cincinnati College of Medicine, and The Cincinnati General Hospital. This study was aided by two grants made in honor of Craig Yeiser. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byNATURAL HISTORY OF 338 TREATED AND UNTREATED PATIENTS WITH STAPHYLOCOCCAL SEPTICÆMIAFifteen years' experience with staphylococcus septicemia in a large city hospitalSulfathiazol and sulfamethylthiazol in the treatment of pneumonia 1 January 1941Volume 14, Issue 7Page: 1137-1154KeywordsBloodHospital medicineMortalityOsteomyelitisRiversSepsis ePublished: 1 December 2008 Issue Published: 1 January 1941 PDF downloadLoading ...