Answers are grounded in this paper and cite their sources.
Utilizing immunocytochemistry numerous macrophages were localized in regressing corpora lutea. In contrast, few macrophages were observed in young corpora lutea. Regressing corpora lutea readily produced TNF-a in vitro in response to lipopolysaccharide, whereas young corpora lutea produced significantly less TNF-a. T lymphocytes were identified in young corpora lutea preceding the appearance of macrophages. These observations suggest that cells of the immune system and cytokines could be important participants in physiological regression of the corpus luteum.
No takes yet. Share an insight, caveat, or question.
Bagavandoss et al. (1988) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: