Why the study?
Does responsiveness to intravascular fluid administration, predicted by ultrasonographic measurement of the inferior vena cava, impact survival in patients with cancer in the intensive care unit?
Does responsiveness to intravascular fluid administration, predicted by ultrasonographic measurement of the inferior vena cava, impact survival in patients with cancer in the intensive care unit?
In ICU patients with cancer, responsiveness to intravascular volume expansion did not significantly improve survival.
Fluid responsiveness was not associated with lower mortality in cancer ICU patients; leaves open whether IVC ultrasound should guide volume expansion.
We conducted an observational, longitudinal prospective study in which we measured the diameters of the inferior vena cava (IVC) of 47 patients using ultrasonography. The aim of our study was to assess the state of blood volume and to determine the percentage of patients who responded to intravascular volume expansion. Only 17 patients (36%) responded to fluid management. A higher number of responding patients had cardiovascular failure compared with nonresponders (82% vs. 50%, P = 0.03). Among the patients with cardiovascular failure, the probability of finding responders was 4.6 times higher than that of not finding responders (odds ratio, 4.66; 95% confidence interval, 1.10–19.6; P = 0.04). No significant difference was observed in the mortality rate between the two groups (11% vs. 23%, P = 0.46). In conclusion, responding to intravascular volume expansion had no impact on patient survival in the intensive care unit.
No takes yet. Share an insight, caveat, or question.
Ñamendys‐Silva et al. (2016) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: