Answers are grounded in this paper and cite their sources.
In addition to hyperresponsiveness in asthma, airway smooth muscle (ASM) also manifests an inflammatory phenotype characterized by augmented expression of mediators that enhance inflammation, contribute to tissue remodelling and augment leucocyte trafficking and activity. Our present review summarizes contemporary understanding of ASM‐derived mediators and their paracrine and autocrine actions in airway diseases. LINKED ARTICLES This article is part of a themed issue on Respiratory Pharmacology. To view the other articles in this issue visit http://dx.doi.org/10.1111/bph.2011.163.issue‐1
No takes yet. Share an insight, caveat, or question.
Damera et al. (2010) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: