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June 1, 1966The Journal of PhysiologyOpen Access

Onset of contractility in cardiac muscle

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Population

Rabbit or cat papillary muscle

Design

Preclinical

Authors

ABAllan J. Brady

Discussion

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Overview

Supports further mechanistic studies in cardiac muscle; leaves open translation to human physiology or practice.

Structured PICO

P
Population
Rabbit or cat papillary muscle
I
Intervention
Quick stretches and releases of controlled velocity, amplitude and time of onset
O
Outcome
Onset of contractility (tension development and shortening velocity)surrogate

This preclinical study demonstrates that the onset of contractility in cardiac muscle is relatively slow, reaching maximum shortening capacity midway through the rising phase of isometric tension.

Cite This Study

Allan J. Brady (1966) studied this question.

synapsesocial.com/papers/6a213713c462d13b4dc3bae7https://doi.org/10.1113/jphysiol.1966.sp007931
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