Key result
Cryoballoon ablation provides an effective means of achieving pulmonary vein isolation, with potential advantages over standard radiofrequency ablation based on its biophysics and biomechanics.
This review provides a comprehensive overview of the biophysics and biomechanics of cryoballoon ablation for pulmonary vein isolation, highlighting practical aspects for clinical electrophysiologists.
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Informs AF ablation choices for electrophysiologists; leaves open randomized confirmation of advantages over radiofrequency.
Recent clinical and preclinical studies have demonstrated that cryothermal ablation using a balloon catheter (Artic Front®, Medtronic CryoCath LP, Pointe-Claire, Canada) provides an effective means of achieving pulmonary vein isolation. This review explores the biophysics and biomechanics of cryoballoon ablation. Components of the cryoballoon catheter system are examined, mechanisms of cryothermal injury are summarized, and potential advantages of cryoballoon technology over standard radiofrequency ablation in isolating pulmonary veins are discussed. Practical aspects of biophysics and biomechanics relevant to the clinical electrophysiologist are emphasized, particularly with regards to the selection of the most appropriate cryoballoon catheter and minimizing peri-procedural complications.
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Andrade et al. (2012) conducted a review in Pulmonary vein isolation. Cryoballoon ablation vs. Standard radiofrequency ablation was evaluated. Cryoballoon ablation provides an effective means of achieving pulmonary vein isolation, with potential advantages over standard radiofrequency ablation based on its biophysics and biomechanics.
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