Key result
MyomiRs are crucial regulatory elements for cardiovascular development and serve as promising diagnostic biomarkers for the early diagnosis of cardiac disorders.
Why the study?
MyomiRs are crucial regulators of cardiovascular development and promising diagnostic biomarkers, warranting a summary of recent findings on their epigenetic modulations and role in cardiac regeneration.
This review highlights the role of MyomiRs in cardiovascular development, myocardial remodeling, and their potential as diagnostic biomarkers for cardiac diseases.
No immediate practice change; extends myomiR literature but leaves open prospective validation.
Muscle-specific miRNAs, which are known as MyomiRs, are crucial regulatory elements for cardiovascular development. MyomiRs are abundantly expressed in the myocardium and regulate certain aspects of physiological and pathological processes in myocardiocytes, including cardiovascular development, myocardial remodeling, and arise for cardiovascular diseases through different mechanisms, such as epigenetic pathways. Clinical and experimental studies have confirmed the myomiRs as promising diagnostic biomarkers for the early diagnosis of cardiac disorders. In this review, we have summarized recent findings in the field of epigenetic modulations of myomiRs and cardiac regeneration associated with cardiac diseases.
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Abkhooie et al. (2020) conducted a review in Cardiac diseases. MyomiRs was evaluated. MyomiRs are crucial regulatory elements for cardiovascular development and serve as promising diagnostic biomarkers for the early diagnosis of cardiac disorders.
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