Key result
Chinese Oral Anticoagulants Knowledge Tool effectively discriminates anticoagulant knowledge across key populations.
Why the study?
To develop and validate an oral anticoagulant knowledge tool for Chinese-speaking patients treated with warfarin or direct oral anticoagulants (DOACs) in Hong Kong.
Cross-Sectional (n=200)
No
Absolute Event Rate: 90% vs 51.55%
p-value: p=<0.001
The C-OAKT is the first validated Chinese-language tool to effectively assess patient knowledge regarding both warfarin and DOACs in an ambulatory care setting.
Facilitates knowledge assessment in Chinese anticoagulant users; leaves open whether higher scores improve adherence or outcomes.
To develop and validate an oral anticoagulant knowledge tool for Chinese-speaking patients treated with warfarin or direct oral anticoagulants (DOACs) in Hong Kong. This pilot validation study consisted of the following three phases: (1) the development of a knowledge tool and content validity assessment; (2) a pilot study of 200 participants, consisting of 100 patients taking warfarin or DOACs, 50 pharmacists, and 50 members of the general public; and (3) known-group validity and reliability assessments. A 19-item “Chinese Oral Anticoagulants Knowledge Tool (C-OAKT)” was developed with a scale content validity index of 0.95. The mean score for known-group validity was significantly higher in the pharmacist group than the patient groups, and the patient groups scored significantly higher than the general public (mean ± standard deviation [SD] = 90.00 ± 7.11 vs. 51.55 ± 17.49 vs. 19.0 ± 15.42, respectively; p < 0.001). The mean score was higher for patients who attended a pharmacist-managed anticoagulant therapy management clinic (PAC) than for non-PAC patients (mean ± SD = 56.80 ± 13.60 vs. 46.30 ± 9.43; p = 0.004). An analysis of internal consistency showed a Cronbach's alpha value of 0.86. The results of the pilot validation study suggested that the C-OAKT is a valid and reliable instrument for assessing patients' knowledge of oral anticoagulants in ambulatory care settings. This is the first validated Chinese version of an anticoagulant knowledge assessment tool. This tool will be utilized in public hospitals in Hong Kong, and will facilitate future research exploring the relationship between anticoagulant knowledge and patient-related outcomes.
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Chan et al. (2023) conducted a cross-sectional in Patients on oral anticoagulants, pharmacists, and general public (n=200). Chinese Oral Anticoagulants Knowledge Tool (C-OAKT) was evaluated on Known-group validity (C-OAKT score) (p=<0.001). The Chinese Oral Anticoagulants Knowledge Tool successfully discriminated knowledge levels, with pharmacists scoring higher than patients and the general public (90.00 vs 51.55 vs 19.0, p<0.001).
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