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September 24, 2020Journal of Medicinal ChemistryOpen Access

Potent and Selective Human Prostaglandin F (FP) Receptor Antagonist (BAY-6672) for the Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Hartmut Beck Tobias Thaler Daniel Meibom Mark Meininghaus Hannah Jörißen Lisa Dietz Carsten Terjung Michaela Bairlein Clemens-Jeremias von Bühler Sonja Anlauf Chantal Fürstner Timo Stellfeld Dirk Schneider Kersten M. Gericke Thomas Buyck Kai Lovis Uwe Münster Johanna Anlahr Elisabeth Kersten Guillaume Levilain Virginia Marossek Raimund Kast

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Abstract

efficacy in a preclinical animal model of lung fibrosis, thus paving the way for a new treatment option in IPF.

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Beck et al. (2020) studied this question.

synapsesocial.com/papers/6a214c83bd959c3a83ab9823 https://doi.org/10.1021/acs.jmedchem.0c00834

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