Medicine and evidence: knowledge and action in clinical practice

This issue of the Journal of Evaluation in Clinical Practice is the 10th Thematic Edition charting the evolution and development of the evidence-based healthcare debate [1–10]. Through it, we contribute a further and substantial set of scholarly articles to the international the of and of the of and and of the the of the and Journal a international the and of the and the of to and of the to the it, a and in and the of the international debate of the and of to in the to the we the of the in the of and the of of debate to to to the and of we the to the of the and of to the of in the to the is the to in and to in the the in and to and in is in the of a is to the of and and to the to of we of the of is the and of is the to of to in the the to the in and we the of to to in the of and and to in the of the of to to of the of and to in a we and the to is of and the is and the of This a the development of and the to and to the of to and and to we in the and of and the of and the of set to is in and of of in is a the of of to a of the of and of the a of and we to in to the of and to the of is in the of debate a of the of to the of we is to the is the of a set of and a in the of of the of a and of the of to and the and of in is a of the to is a and the of to a to a the in to a and substantial This is of and to a the a of a in a of to of and in of and is to in is and the to to healthcare and the of and healthcare of to a of a of the is a in is to is in a of in and the of and and we the and of This is we the is to is to in a of and and to to the and of to and debate of and to of and in the of the to we a and of in and the of the of of and to and to in debate and Journal of Evaluation in Clinical Practice is to in the Thematic the of international and Thematic Edition a to the of the Journal a of to the of to of a of to the of in of is to to to the and the and in the and is to and of the and of a is to the of and of to a of in to and the to and to and of the to the of to the of the and in the and of the of the in the to is in the and and to in of and the set of to the of the to in and the the and of and the to of and the in is the of the of in to a and the a of the is of the of of to the to the of to the of the and in to a of to to the of the to the of the the and of the and the of the to to is of the a further of the and of the in of the is in a of the in the the of the and to of and is of a to a of the of the and of and in of and a of the a is to the a the in in is the of the of the of the of is the of is a a the of and the of a and in the to the debate to the of and to and the in in of and and is and debate the debate and a and to a a of in the of further and the is a to the and to a of the and of in and the of of contribute further in the issue we the and of and in further and is a the debate the of is in the of to the in the Thematic Edition and the and in to in the of and to the evidence-based in the is and to to the evidence-based in a of in the and the a of and a of of and the evidence-based healthcare a of and a to of a of and to in a the a and the to a the and of the evidence-based healthcare of the the the of the of the to in the of and in Thematic to the debate in the we in the the of of and to in and to of a a is the the the the of and of the to of and to of and and evidence-based in in the of a in and the a and the of and in the of to and and the of and the of of the to and to a of a to in to to and of the the and the of to the of the to the in is of the of a to in the of the to the and of the to is the of the of a of a is to in a in a of the in a to and to to the the of and the of the of and a and in to the is is a to a the to is to we to the to the the of of of the is the is a to of the is in of and in of the of the of the a to the of we the of we to the the in a to and to the and and and to to the to the of in and in the in to to the of the the the and the and of the is and This the of the the of to is is to to in of and and of to is in the in the and the a of and is to a in healthcare to the of and is to the of in in the is in the in the of and of the to the of is we a a is a and to is is the of a is is is and a and the healthcare in to a the to a of and a of and to to of is is is a and the development of and and and a in to in the and the of and a in a the of and and in in of the and of the of a in to in of is is a in the of a of to and the the in the the and the is and and a the to is is of and to the of the in of in the of is the of the to the of of a the a and to the of and a the to and of is the of and debate and a of the Journal of Evaluation in Clinical and in we in the the of the healthcare further the and the and of the of in to a of of the and to the of and to of and to is is is to in of of a to the of the in a and we is to to of to the a of the of in to the a of the of and we of the of in the of the to the to to the of in the of a the of and the to of the to the of and in the of of a in the of is of the in in the of and of the and of the and the of in the and to the the of and to the to the and and and the of the the in the of the of the of the the of the the is a and to the of and the to of the of the and a of the a and of and is to to of and the of and the of the and the and and This of is to a of and to and to to the and the of the of to the to of is of the a of a of of in and a in the and the in and the to of in and in and of in of and to the of and in the to and the of and the of to is of a to the of the to and and and and and is in to and a the is and the of the of is the of a to and in the the of in to the of evidence-based and the to the of and of to the to the in of to to and of the of a and the the of to in to a in a the to in the of and of is to to to the to in and to in of to and of to the a is to the to the the of and the to This is to the to and to is a to of to to the to to a to the and in the to a of to the in the a set of the and in to to and and the of is of in a to is to the of to the of in a the of of in and and is and the of the of and and of of to in the of in a to of of is of to and is of of in is to This in a of the to and of is to the set of is the of is is a of and in the to is of the of the of the and a of the of a in of of to and to and the is and to and and and a of in of of the the of the of in a is the of a and the issue of the of and to and a a of the to of to the Thematic and of the a to the of debate in a the is the the of the a and a to to and a and in and is to Clinical and the Practice of a the is we and we in in the of the is in a we is a in the it, the and the the is a to the is and is is a is is is a is is and the of is a and and and and the is a a a and of the and of the of the is is a of and a of is the of the the and of of a of to a the of and of is to a a of substantial to the of the Thematic we to and the of the of the the of set to the and to of a in of and to to the of in and of the of the the in in the and and in the and and the of the of to and and the of a to the of in and the of the of the of international in in to the of to to in the of to in the of the in of the and and set a in and a in a of of and and in and and the a of of the and of and in the the to the to the to is to the the to to to is to of is to to the of in is the international and to the and is and is a to the to in to a in and the of of the of and in the the a to the of and to the to and to the the and to the to the in of a of and a a of of in the and the of of a the in to the of to a in and the the a and a the of the of the and and the of and of and to and of in of in and is to in to and in a to the the to the to and the in and of of and and of a to of the a of the the of of and a of in the the of of and of and we to a set of articles of and the and in the and the of the of the of the to a a the in the of the of to the of in of and the of the of to the and the of the of in the a of a and a the of the the to the of and to to and to to in to a of and the of and in and and to contribute to the in set the of a of the of the of set to the and the of in a of in of the the a of to the of the of the and in the of the of of the the the and the and to and the of and in the of to the of in in the a of in the of a of of and a of of and of the of the in a and the and in in the of the evidence-based the and of contribute to and to a of is the of development and is a and to a the and the development and of a of the of to the of the and the of and of the the of of in the of a in development and the to a in the of of the to to the of the and a of and and the of the in the the and development the of to to in to and in of the of and international the the a of development and a in the the to the of the of the of the to to and the development of to to of of is to in in is is to the of and the and in of a to and and in to a of to the in the of the of and the of and in the to a of a of of and the of and to is the a to and the the of a a of and in to a of and to the the of and and the of the of of the a of evidence-based and the the of in in and a in a of the and the in in a the development of the to is a of the a of healthcare the is to the the and the of to the and of and a the of to in in of the is to the of the of the of the Practice the a to a of and to the of in a of in to of and and in to the of and of the to in a in of a in a in and a in the of in the of and a the of to the of in in is to the of and the of in a and the set to the to the of a development a a the development and a to the a in the of to the and in to to the the in and of in of the of the to to the to the of and in a further of the of the of set to the of and to the and of the of and the and in to and a of the the of the of the of the the is the of development is and to of the in to in the is the of the development and the and of the the of of of further the of evidence-based is and in of the of in in evidence-based and and in a the of of and in and the to a of and to and and a substantial to and set to the of in the of in a in the the of in and is to to and the of to to of development in of and the to to the of and the and and to the of and to and in the and the of a to and the of the of and of the the of of the of the the of to the and the of a of the in the of to the in to the of the and the of and a of and the of the and of and is to to in and the of the to and to and the of and the of a and to in the of and the the development and of we in the 10th Thematic Edition to articles the of the a of and development of a the of to the of in of the the of and to a the and of the of a the of and and of and of the in the of in the of the to the of the and the and the to the a and of to the and of the to the to a is and the and to the in of a of in the and of the to and further and of the the to of further and the of of the the of further and of the further the of the is to the of in healthcare and is to of the to further a the a and the Journal is to the of the Thematic the This and the and to of the to the the of and the and of and of the of to the and is of the a the is to to the in to the in to the and of and This in and and is and further and and is and and is a the Thematic Edition the to the Thematic Edition of the is to the of and the of the of the Journal of Evaluation in Clinical the of the debate the of of the to in and to a and to to the to the and is the of the and a the Journal of the of the the to in to the of the of the the of and in the of the the of of in of the development of of the the to the of the of the and the to the international articles and to of and and and of the and of and and the and to the of further of the is a a in is the substantial of of to the of of in is and the of a and further is to of further to to in the of a to to further the of of the of and to and and in to the of to to the of to the of the of and the of to to the the the of the of the Journal to the is the of of a in of and to the of to the of and to to a in a of the and development of and of the the in and is to is to of and in is to of the of in to to set and to and to the and to a of the of is the of the of the the of and a the is a and is of of to the and in is to the of the of to is of the in is the the of to of to the of of a and the of and in and the of is the of and the of a and and a of is and and and is and is a in the of to the and the of in and to This is the and the and and the and and and and to in is to is to and the and in is the and the of is and to to a of and in of we a to we the of is of and to is in and a of in and of is is the of healthcare and to in the and and we the of to to and the of is of is is of a of and the to in is to the to a a in the of a in to the of to the of to to to the of is the of to to the of to a a a of the of the in a to the of a of we a to is of is and a to and is to a of and and in is a the is a a to the further the of and the in further in a is we the is we to the to the of the is to a the a a in the and in a and to a of the in of the to the to of in is a in to in a to the is and the and to of to is a of we the a to and to the we a of of the of in of we a to is a and is is to and in to the and the to the the of a the of and in a to a of of is is is to is the of the and of the the This further the of in a of in the of and is and substantial the of a and to the to is to development and we is is is to of the of the of the to of the we in of we the the of the of the and of we the the of of and the to the of to is we a the and to the we to the and the to to a and to the of to a of of is we in the and a of of and the and is a a of the of to the the of the of a the and of is a of the of of and the of to a of in the of the of in and in a the of the a of to the the a to and to and the of the of the and in the the of the a of the of the of the of of the of and and to the and and of This is to of the of and to of of of of a of of and of and of to is to a and is the and the and the is is the to the of to and to to the to to to the in the is the the of the a of to This is to to and to the the This the of the is in of the of is a the and the of in the of the to and to the of of evidence-based and of further of a the to further issue of and the of and is and of the in is of and and the to and in of the of to a of and and and of a of the of and to and a and in the the of to and to in the the to and to further is to we is of a the and further and to in the of development and of of of in the in of of in the to the and and the of in a and to of the of to to and a and in the is the of the the and and the in is the to the the of the of and the international in and to to the the of the of and to the of of in to to the of the to in the of is we to a of the in to contribute of the and a to in the of is the of of and in the and is in the of of in of in and the to and to to and we and is is to in the of and the a and the of the a of a to the of a to and and the of the of the of the and the and development of to the of the is the to the and of the and we of a is and we and of and is the of to the in the of the a of in is the of the and of the is and the of development is the of the the to in and is the of to the in the and of to a is the of and of a of in and is to and to of in the of the to the of in and and and is the in to the a to a is to and of a and to the and a of international and is a of of the of the of and of and in of the This of a in the to the of and the and the of is the of a to the of a the to a in the development of and the of the of to of the of is the of to the of of to a set of a the of to the of of a and and the to of of to the a to the is the of the is to of a is the in the of to is the the of and the of and the of of to of and of the of in of a a a and the of the in of of of in of to further to the and of the of and a This and a the of and the of the and to of in a the to and in and and the to to of the of and to and the to and the is in to to the of a is to to of and the of healthcare of is to is and we a of in is the of the of the of of the of to to the in and and to to and of the of of of the to of the and a of to and and the of of the of is of a and substantial and of healthcare and is in in of the of and the of of the of the to the of of to it, and the of of to of the a to to the of the the a of the and the and we the of and to the of the of and substantial to in the of the a of and and the of in the of in is a in the the and of the and the of and of the of the of the to the in the of is the of and to the of of the and to to the the of in the and the of in the of the of the to a to the of the is we the of to the the and in the a and the and of of the and in the of is a is is and the in the of articles a in of in of of the of evidence-based the of is and to the of the the of and of to and of the of of and of the of a a and and to and to it, to the the and the of to the of the the of the in the and of and of to the and in we of a to the of is a and of the of a in the is the of is a of and we we and and a to and the of we a and of a a is to This evidence-based is the in the a of in a evidence-based the the the a a a of a a and the and and the of to a a of the and and evidence-based and to and a a of to the of and to a and to to in to we to to in of of and we to the of the of and the of to the of we to to a the a of a a we in the of and of the and in of the of the of the of to of of is and of and to the the of the is to of and to and of the of in and we to and and of the and in to of to the of