The prevalence of chronic kidney disease was 17.3% in prehypertension and 22.0% in undiagnosed hypertension, compared with 13.4% in adults with normal blood pressure.
Cross-Sectional (n=17,794)
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What is the prevalence of chronic kidney disease across different blood pressure categories, including prehypertension and undiagnosed hypertension, in US adults?
Chronic kidney disease is highly prevalent even in individuals with prehypertension and undiagnosed hypertension, highlighting the need for early identification and treatment.
Odds Ratio: 2.37 (95% CI 2–2.81)
Tasa de eventos absoluta: 22% vs 13.4%
Hypertension is both a cause and a consequence of chronic kidney disease, but the prevalence of chronic kidney disease throughout the diagnostic spectrum of blood pressure has not been established. We determined the prevalence of chronic kidney disease within blood pressure categories in 17 794 adults surveyed by the National Health and Nutrition Examination Survey during 1999-2006. Diagnosed hypertension was defined as self-reported provider diagnosis (n=5832); undiagnosed hypertension was defined as systolic blood pressure > or = 140 mm Hg or diastolic blood pressure > or = 90 mm Hg, without report of provider diagnosis (n=3046); prehypertension was defined as systolic blood pressure > or = 120 and or = 80 and 30 mg/g. Prevalences of chronic kidney disease among those with prehypertension and undiagnosed hypertension were 17.3% and 22.0%, respectively, compared with 27.5% with diagnosed hypertension and 13.4% with normal blood pressure, after adjustment for age, sex, and race in multivariable logistic regression. This pattern persisted with varying definitions of kidney disease; macroalbuminuria (urinary albumin:creatinine ratio >300 mg/g) had the strongest association with increasing blood pressure category (odds ratio: 2.37 95% CI: 2.00 to 2.81). Chronic kidney disease is prevalent in undiagnosed and prehypertension. Earlier identification and treatment of both these conditions may prevent or delay morbidity and mortality from chronic kidney disease.
Crews et al. (Tue,) conducted a cross-sectional in Chronic kidney disease and hypertension (n=17,794). Undiagnosed hypertension and prehypertension vs. Normal blood pressure was evaluated on Prevalence of chronic kidney disease (OR 2.37, 95% CI 2.00 to 2.81). The prevalence of chronic kidney disease was 17.3% in prehypertension and 22.0% in undiagnosed hypertension, compared with 13.4% in adults with normal blood pressure.