Key result
Hypertensive pregnancy disorders were associated with a 2.134-fold increased risk of future stroke compared to women without such disorders.
Why the study?
Female stroke incidence is rising and occurring at younger ages, but few studies have evaluated stroke risk following hypertensive pregnancy disorders in Asian women.
Do hypertensive pregnancy disorders increase the risk of future stroke in pregnant women?
Case-Control (n=167,480)
Do hypertensive pregnancy disorders increase the risk of future stroke in pregnant women?
Hazard Ratio: 2.134 (95% CI 1.817–2.505)
Absolute Event Rate: 0.47% vs 0.56%
p-value: p=<0.001
Hypertensive pregnancy disorders are associated with a more than two-fold increased risk of future stroke in Asian women.
No takes yet. Share an insight, caveat, or question.
May warrant enhanced stroke surveillance postpartum; extends prior associations to Asian women but leaves causality open.
Huang et al. (2020) conducted a case-control in Hypertensive pregnancy disorders (n=167,480). Hypertensive pregnancy disorders vs. Women without hypertensive pregnancy disorders was evaluated on Any episode of stroke (excluding peripartum and postpartum strokes within 3 months) (HR 2.134, 95% CI 1.817-2.505, p=<0.001). Hypertensive pregnancy disorders were associated with a 2.134-fold increased risk of future stroke compared to women without such disorders.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: