Population
Bovine calf pulmonary artery (in vitro model)
Comparison
Nitroprusside vs Nitroglycerin or control conditions without…
Design
Preclinical
Authors
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Does not alter nitrovasodilator practice; hypothesis-generating for NADH oxidoreductase-mediated nitroprusside activation in pulmonary arteries.
A membrane-bound NADH oxidoreductase in the pulmonary artery is responsible for activating nitroprusside to release nitric oxide and mediate arterial relaxation.
Mohazzab-H. et al. (1999) studied this question.
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