Why the study?
Acute mental stress increases arm BP, but whether a stress-induced pressor response also occurs in other vessels remains unclear.
Does acute mental stress increase ankle blood pressure in young healthy men?
Comparison
5-min mental stress task vs control task
Design
Pilot study
Follow-up
30 min after the task
Key result
Acute mental stress significantly increased ankle systolic blood pressure compared to a control task (interaction P < 0.001), with elevations sustained for 30 minutes post-stress in young healthy men.
Authors
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Acute mental stress may elevate ankle BP beyond brachial measures; hypothesis-generating for peripheral vascular responses and requires confirmation in larger studies.
RCT (n=56)
No
Does acute mental stress increase ankle blood pressure in young healthy men?
Absolute Event Rate: 137% vs 132%
p-value: p=<0.001
Acute mental stress induces a sustained elevation in ankle blood pressure in young healthy men, indicating a systemic pressor response beyond just the arm.
Kume et al. (2022) conducted an RCT in Healthy (n=56). Acute mental stress (mental arithmetic) vs. Control task (slowly counting upward) was evaluated on Ankle systolic blood pressure at 30 minutes post-task (p=<0.001). Acute mental stress significantly increased ankle systolic blood pressure compared to a control task (interaction P < 0.001), with elevations sustained for 30 minutes post-stress in young healthy men.