Key result
Systolic motion of the interventricular septum on ventriculograms was similar in patients with atrial septal defect and controls, with the cephalic third moving anteriorly in 9 of 13 vs 3 of 7 patients.
Why the study?
What is the anatomical basis for abnormal systolic interventricular septal motion seen on echocardiography in patients with atrial septal defect when compared to ventriculography?
Observational (n=20)
What is the anatomical basis for abnormal systolic interventricular septal motion seen on echocardiography in patients with atrial septal defect when compared to ventriculography?
The study suggests that echocardiographic abnormalities of septal motion in ASD result from end-diastolic septal flattening or bowing into the left ventricle, rather than true abnormal systolic motion.
End-diastolic septal flattening likely explains echo abnormalities in ASD rather than systolic motion; leaves open prospective validation of imaging discordance.
Abnormal systolic interventricular septal motion is an echocardiographic manifestation of right ventricular volume overload. In order to determine the anatomical basis for this echocardiographic finding, septal motion recorded by left lateral or left anterior oblique ventriculograms was compared with echocardiography ventricular septal motion. Thirteen patients with secundum atrial septal defects and 7 control patients with trivial or no heart disease were included in the study. We found that on ventriculograms the systolic motion of the interventricular septum was similar in both atrial septal defect and control patients. That is, the cephalic third of the septum moved anteriorly in systole in 9 of the 13 patients with atrial septal defect and in 3 of the 7 controls. The caudal two-thirds of the septum moved posteriorly in all patients. These results are compatible with the theory that argues that the echocardiographic abnormalities of septal motion in patients with atrial septal defect result from an end-diastolic septal flattening or bowing of the septum into the cavity of the left ventricle.
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Mueller et al. (1978) conducted an observational in Atrial septal defect (n=20). Secundum atrial septal defect vs. Control patients with trivial or no heart disease was evaluated on Anterior systolic motion of the cephalic third of the interventricular septum on ventriculograms. Systolic motion of the interventricular septum on ventriculograms was similar in patients with atrial septal defect and controls, with the cephalic third moving anteriorly in 9 of 13 vs 3 of 7 patients.
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