For ultrasound-guided prostate biopsy, a transperineal approach is emerging as a superior alternative to the transrectal approach because the former is associated with a lower risk of infection. This pictorial essay aims to highlight the broader applications of transperineal ultrasound (i.e., those beyond prostate biopsy). We demonstrate various diagnostic and therapeutic uses of transperineal ultrasound, including lymph node biopsies, abscess drainage, hydrogel spacer placement for radiotherapy, and penile biopsies. Details of the transperineal approach, including patient positioning and preparation, are described. In addition, the effectiveness and safety of the method are demonstrated. Our results underscore the versatility of transperineal ultrasound and its potential to enhance clinical practice, demonstrating its importance as a minimally invasive technique with significant clinical benefits in various medical contexts.
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Santi et al. (2025) studied this question.
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