Key result
Improved ResUnet outperforms standard segmentation methods with an endocardial Dice score of ~0.93.
Why the study?
Automatic segmentation of the left ventricle from cardiac MR images is essential for early diagnosis of cardiovascular diseases.
Does an improved ResUnet architecture improve the accuracy and efficiency of left ventricle endocardium and epicardium segmentation from cardiac MR images compared to existing methods?
Does an improved ResUnet architecture improve the accuracy and efficiency of left ventricle endocardium and epicardium segmentation from cardiac MR images compared to existing methods?
p-value: p=<0.01
An improved ResUnet architecture provides highly accurate automatic left ventricle segmentation from MR images, which is essential for efficient and quantitative evaluation of cardiac function.
May expedite quantitative CMR analysis in research; extends ResUnet variants but leaves clinical validation open.
Cardiovascular diseases are reported as the leading cause of death around the world. Automatic segmentation of the left ventricle (LV) from magnetic resonance (MR) images is essential for an early diagnosis. An enhanced ResUnet is proposed in this paper to improve the performance of extracting LV endocardium and epicardium from MR images, improving the accuracy of the model by introducing a medium skip connection for the contracting path and a short skip connection for the residual unit. Also, a depth-wise separable convolution replaces the typical convolution operation to improve training efficiency. In the MICCAI 2009 LV segmentation challenge test dataset, the percentages of "good" contours, dice metric, and average perpendicular distance of endocardium (epicardium) are 99.12% ± 2.29%(100% ± 0%), 0.93 ± 0.02 (0.96 ± 0.01), and 1.60 ± 0.42 mm (1.37 ± 0.23 mm), respectively. Experimental results demonstrate that the proposed model obtains promising performance and outperforms state-of-the-art methods. By incorporating these various skip connections, the segmentation accuracy of the model is significantly improved, while the depth-wise separable convolution also improves the model efficiency.
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Xu et al. (2022) studied Left ventricle segmentation from MR images (n=190). Improved ResUnet vs. Other state-of-the-art segmentation methods and ground truth manual annotations was evaluated on Segmentation accuracy measured by percentages of 'good' contours (PGC), dice metric (DM), and average perpendicular distance (APD) (p=<0.01). The improved ResUnet model achieved a dice metric of 0.93 for endocardium and 0.96 for epicardium segmentation, significantly outperforming prior state-of-the-art methods.
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