Why the study?
Left ventricular thrombus can form following ischemic heart disease progression and rarely migrate to peripheral arteries, requiring individualized antithrombotic therapy balancing ischemic and bleeding risks.
Case Report (n=1)
No
In a patient with acute limb ischemia due to left ventricular thrombus and silent CAD, a tailored approach using thrombectomy followed by short-term warfarin and aspirin was safe and effective at early follow-up.
Supports individualized antithrombotic regimens post-thrombectomy in LV thrombus; hypothesis-generating and should not change practice.
Trombus v lev komoe (left ventricular thrombus, LVT) se me vytvoit v dsledku progrese ischemick choroby srden (ICHS), kter me ve vzcnch ppadech migrovat do njak perifern tepny. V tomto lnku popisujeme ppad 58letho mue pijatho do na nemocnice s nhlm nstupem bolesti a necitlivost prav doln konetiny; byla stanovena diagnza akutn ischemie doln konetiny. Neekan se ukzalo, e mu trp i nmou a rozshlou ICHS vedouc k srdenmu selhn se snenou ejekn frakc (heart failure with reduced ejection fraction, HFrEF) a ke vzniku LVT. Jako pina akutn ischemie doln konetiny byla u tohoto pacienta stanovena perifern embolizace trombem. Ke snen monosti rozvoje kardiovaskulrn phody a progrese onemocnn bylo teba zahjit innou antitrombotickou lbu. Pacienti s akutn ischemi doln konetiny a komplexn ICHS a LVT mohou vyadovat kombinaci antikoagulan a antiagregan lby. Proto je teba zvolit individualizovan pstup, kter je zaloen na stanoven rizika ischemie a krvcen u pacienta s clem vce omezit monost ischemickch phod a souasn zabrnit vzniku vznamnch krvcivch phod.
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Ardiana et al. (2025) conducted a case report in Acute limb ischemia due to left ventricular thrombus (n=1). Emergency thrombectomy followed by warfarin and aspirin was evaluated on Clinical outcome and bleeding events.
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