CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract.

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA1996 · 757 citations
2. 2Bacterial DNA induces NK cells to produce IFN-γ in vivo and increases the toxicity of lipopolysaccharides1996 · 427 citations
3. 3Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization1996 · 1,066 citations
4. 4Tumor Necrosis Factor: Alpha and Beta Subtypes Appear in Circulation during Onset of Sepsis-induced Lung Injury1991 · 50 citations
5. 5CpG DNA rescue of murine B lymphoma cells from anti-IgM-induced growth arrest and programmed cell death is associated with increased expression of <i>c-myc</i> and bcl-xL1996 · 185 citations