Blood Groups of Gastric Ulcer and Carcinoma

The earliest attempt to find a relationship between the ABO blood groups and disease was that of Alexander (1921). From a study of 50 malignant neoplasms he concluded that groups B and AB were peculiarly susceptible to various forms of neoplasm and that O was more stable or resistant, but admitted that his figures were too small for the susceptibility of group A to be discerned. He found that neoplasms in B and AB groups were severe and rapidly growing, while those in groups O and A were of low malignancy and of long duration.