Omega-3 polyunsaturated fatty acid supplementation reduces blood pressure but not renal vasoconstrictor response to orthostatic stress in healthy older adults

Figures

• 

  Figure 1. Schematic depiction of the experimental protocol and timeline of the intervention. Shaded area denotes 3‐min periods used for data analysis. LBNP, lower‐body negative pressure.

• 

  Figure 2. Relative changes from baseline in renal vascular resistance during graded lower‐body negative pressure (LBNP) pre‐ and post‐fish oil supplementation in the young (n = 10) and older (n = 10) groups (three‐way repeated measures ANOVA). *Significantly different from −15 mmHg LBNP (P < 0.05). †Significantly different from young (P < 0.05).

• 

  Figure 3. Relative changes from baseline in renal blood flow velocity during graded lower‐body negative pressure (LBNP) pre‐ and post‐fish oil supplementation in the young (n = 10) and older (n = 10) groups (three‐way repeated measures ANOVA). *Significantly different from −15 mmHg LBNP (P < 0.05).

• 

  Figure 4. Relative changes from baseline in (A) mean arterial blood pressure and (B) heart rate during graded lower‐body negative pressure (LBNP) pre‐ and post‐fish oil supplementation in the young (n = 10) and older (n = 10) groups (three‐way repeated measures ANOVA). *Significantly different from −15 mmHg LBNP (P < 0.05). †Significantly different from young (P < 0.05). ‡Significantly different from older −30 mmHg LBNP pre‐fish oil supplementation (P < 0.05). #Significantly different from −15 mmHg LBNP (from 3‐factor interaction; P < 0.05).

• 

  Figure 5. Relative changes from baseline in (A) systolic blood pressure, (B) diastolic blood pressure, and (C) pulse pressure during graded lower‐body negative pressure (LBNP) pre‐ and post‐fish oil supplementation in the young (n = 10) and older (n = 10) groups (three‐way repeated measures ANOVA). *Significantly different from −15 mmHg LBNP (P < 0.05). †Significantly different from young (P < 0.05).