The TTE-measured mPA to AscAo ratio significantly correlated with mean pulmonary arterial pressure (r=0.553, P=0.00152) and predicted PH with 80% sensitivity and 100% specificity.
Observational (n=30)
Does transthoracic echocardiography measurement of the mPA to AscAo ratio accurately predict pulmonary hypertension in adult patients undergoing elective CABG?
TTE-derived main pulmonary artery to ascending aorta ratio correlates significantly with invasive pulmonary artery pressures and offers high specificity for predicting pulmonary hypertension.
Effect estimate: r=0.553
p-value: p=0.00152
Background Owing to the nonspecific and subtle nature of physical signs and symptoms of pulmonary hypertension (PH) in early stages, treatment is usually delayed despite advancement over the past decade. Use of transthoracic echocardiography (TTE) as the initial noninvasive modality in the screening and evaluation of PH can provide key information about the etiology and the prognosis of PH, thereby avoiding the complications associated with the invasive methods. The aim of this study was to determine the usefulness of main pulmonary artery (mPA) and ascending aorta (AscAo) ratio using TTE. Patients and methods In this prospective observational study, 30 adult patients undergoing elective coronary artery bypass grafting surgery were enrolled. Postanesthetic induction mPA and AscAo transverse diameters were measured using TTE. The mean pulmonary arterial pressures (mPAPs) were recorded using a direct pulmonary artery puncture after sternotomy. Correlations were established using the Pearson correlation coefficient. Sensitivity, specificity, positive predictive value, and negative predictive value were calculated. Results mPA : AscAo ratio demonstrated significant linear correlation with mPAP (i.e. r=0.553, P=0.00152). Sensitivity, specificity, positive predictive value, negative predictive value were 80, 100, 80, and 100%, respectively, for an mPAP of up to 25 mmHg. Conclusion TTE-guided measurement of mPA : AscAo ratio can be used as a simple and easily reproducible noninvasive method in predicting PH not only in cardiac but also in other noncardiac settings.
Choudhury et al. (Tue,) conducted a observational in Pulmonary hypertension (n=30). Transthoracic echocardiography measurement of mPA to AscAo ratio vs. Direct pulmonary artery puncture was evaluated on Correlation of mPA:AscAo ratio with mean pulmonary arterial pressure (mPAP) (r=0.553, p=0.00152). The TTE-measured mPA to AscAo ratio significantly correlated with mean pulmonary arterial pressure (r=0.553, P=0.00152) and predicted PH with 80% sensitivity and 100% specificity.