Key result
Postischemic reperfusion during cardiopulmonary bypass increased transcardiac veno-arterial IL6 levels (from 0 to 7 pg/ml; p<0.05) and led to sequestration of activated neutrophils and platelets.
Why the study?
Does postischemic reperfusion during cardiopulmonary bypass induce acute cardiac inflammatory responses in patients receiving coronary bypass grafts?
Observational (n=12)
Does postischemic reperfusion during cardiopulmonary bypass induce acute cardiac inflammatory responses in patients receiving coronary bypass grafts?
Postischemic reperfusion during cardiopulmonary bypass triggers an acute, localized cardiac inflammatory response involving IL-6 release and leukocyte-platelet sequestration.
May signal localized cardiac inflammation in CABG reperfusion; hypothesis-generating for targeted interventions.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Stefan Zahler (1999) conducted an observational in Coronary bypass grafts (n=12). Postischemic reperfusion during cardiopulmonary bypass vs. Before onset of CPB was evaluated on Transcardiac veno-arterial difference of IL6 (p=< 0.05). Postischemic reperfusion during cardiopulmonary bypass increased transcardiac veno-arterial IL6 levels (from 0 to 7 pg/ml; p<0.05) and led to sequestration of activated neutrophils and platelets.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: