Key result
Patients with prior coronary artery bypass grafting exhibited paradoxical left ventricular wall motion, characterized by smaller septal and larger lateral radial displacement compared to healthy controls.
Observational (n=17)
MRI tagging reveals that paradoxical septal wall motion after CABG is primarily due to rigid-body translation of the entire heart rather than a localized loss of myocardial contractility.
Paradoxical septal motion post-CABG may reflect rigid-body translation rather than regional dysfunction; leaves open whether this alters wall-motion interpretation in clinical practice.
The left ventricular wall motion during systole was investigated from a mechanical point of view by using a magnetic resonance tagging technique. Subjects were seven patients with coronary artery bypass grafting (CABG). At first, in order to evaluate the cardiac contractility in each patient, the circumferential strain in myocardial wall was analyzed. It was found from there results that the circumferential strain in four patients decreased compared with that in healthy humans. Next, the paradoxical wall motion in patients with CABG was quantitatively described by calculating the displacement. The results showed that the radial displacement of septal wall in the patients was smaller than that in healthy humans, and the radial displacement of lateral wall was larger. Furthermore, anterior wall and posterior wall moved toward septal wall. Such left ventricular wall motion was recognized in even the patients with normal cardiac contractility. Therefore, it was considered that the paradoxical wall motion in the patients with CABG was not caused by a drop of the cardiac contractility, but a rigid-body motion of the heart.
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INABA et al. (2005) conducted an observational in Coronary Artery Bypass Grafting (n=17). Coronary artery bypass grafting vs. Healthy humans was evaluated on Left ventricular wall motion (circumferential strain and radial displacement). Patients with prior coronary artery bypass grafting exhibited paradoxical left ventricular wall motion, characterized by smaller septal and larger lateral radial displacement compared to healthy controls.
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