Why the study?
In patients with acute myocardial infarction without significant epicardial CAD, the aetiology of myocardial necrosis is not immediately apparent, data regarding therapeutic strategies are limited, and identifying the underlying pathophysiological mechanism is crucial for prognosis and therapy.
Case Report (n=1)
No
Systematic investigation of MINOCA patients using intracoronary provocation tests can unmask underlying dynamic coronary tone abnormalities, enabling targeted and effective pharmacological therapy.
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D’Amario et al. (2019) conducted a case report in Myocardial infarction with no obstructive coronary arteries (MINOCA) (n=1). Intracoronary acetylcholine was evaluated on Elicitation of coronary spasm.
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