Key result
Insulin sensitivity was negatively correlated with common carotid maximum intima-media thickness in both high-risk (r = -0.45, P<0.05) and low-risk (r = -0.59, P<0.01) men.
Why the study?
Is insulin sensitivity associated with common carotid intima-media thickness in men at high and low coronary risk?
Cross-Sectional (n=48)
Is insulin sensitivity associated with common carotid intima-media thickness in men at high and low coronary risk?
Effect estimate: r = -.45 (high-risk), r = -.59 (low-risk)
p-value: p=<.05 (high-risk), <.01 (low-risk)
Increased carotid intima-media thickness, an early marker of atherosclerosis, is negatively associated with insulin sensitivity even in men without diabetes.
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May mark insulin resistance as atherosclerosis risk factor in nondiabetic men; leaves open causality and intervention effects.
Agewall et al. (1995) conducted a cross-sectional in High and low coronary risk (n=48). Insulin sensitivity was evaluated on Relationship between insulin sensitivity index and common carotid maximum intima-media thickness (r = -.45 (high-risk), r = -.59 (low-risk), p=<.05 (high-risk), <.01 (low-risk)). Insulin sensitivity was negatively correlated with common carotid maximum intima-media thickness in both high-risk (r = -0.45, P<0.05) and low-risk (r = -0.59, P<0.01) men.
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