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February 1, 2003Cancer Biotherapy and Radiopharmaceuticals

Targeting bcl-2 by Triplex-Forming Oligonucleotide—A Promising Carrier for Gene–Radiotherapy

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Authors

CSChangxian ShenThe Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research InstituteDRDirk RattatUmicore (Belgium)ABAndreas K. BuckUniversity of Würzburg

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Shen et al. (2003) studied this question.

synapsesocial.com/papers/6a22306ba9754429c0e21996https://doi.org/10.1089/108497803321269296
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  1. 1Unambiguous demonstration of triple-helix-directed gene modification2000 · 66 citations
  2. 2Gene activation by triplex-forming oligonucleotide coupled to the activating domain of protein VP161999 · 48 citations
  3. 3Induction of Apoptosis in Small-Cell Lung Cancer Cells by an Antisense Oligodeoxynucleotide Targeting the Bcl-2 Coding Sequence1997 · 219 citations
  4. 4Differential effects of Bcl-2 on T and B cells in transgenic mice.1992 · 136 citations