Key result
In women with congenital heart disease, pregnancy-induced worsening of NYHA functional class occurred in 18% of successful pregnancies and was strongly predicted by a baseline NYHA class >1 (OR 127).
Why the study?
Does pregnancy worsen functional status in women with congenital heart disease?
Cohort (n=95)
No
Does pregnancy worsen functional status in women with congenital heart disease?
Pregnancy in women with congenital heart disease is associated with functional worsening, particularly in those with baseline NYHA class >1 and complex CHD.
Answers are grounded in this paper and cite their sources.
May guide preconception NYHA risk counseling in congenital heart disease; leaves open need for prospective validation before practice change.
Background: Pregnancy represents a raising issue in women with Congenital Heart Disease (CHD), but its effect on functional status is not well established. The aim of our study was to assess the probability of modification of functional status due to pregnancy in CHD, thus improving preconceptional counselling.
No takes yet. Share an insight, caveat, or question.
Luciano Daliento (2017) conducted a cohort in Congenital Heart Disease (n=95). Pregnancy vs. Pre-pregnancy baseline was evaluated on Worsening of NYHA functional class from baseline to 6-months after pregnancy (OR 127, p=<0.0001). In women with congenital heart disease, pregnancy-induced worsening of NYHA functional class occurred in 18% of successful pregnancies and was strongly predicted by a baseline NYHA class >1 (OR 127).
Synapse has enriched 10 related papers. Consider them for comparative context: