Kikuchi-Fujimoto disease is a rare disease characterized by persistent fevers, tender lymphadenopathy, hyperinflammation, and histiocytic necrotizing lymphadenitis. It has been described in association with autoimmune disorders, primarily, systemic lupus erythematosus. In this case report, we describe a 33-year-old White woman in whom we recently observed an association between dermatomyositis and Kikuchi-Fujimoto disease who was treated with oral prednisone for a month with complete resolution of symptoms. We highlight the importance of considering this disease in the differential diagnosis for fevers and tender lymphadenopathy as well as the importance of multidisciplinary care and early pathologic diagnosis.
Luan et al. (Mon,) studied this question.