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June 5, 2026Journal of Addiction Medicine

Opioid Agonist Treatment Use Among First Nation Peoples in Ontario, Canada: A Repeated Cross-sectional Study of Prevalence Trends From 2013 to 2023

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Authors

NRNevena RebićSLShaleesa LedlieBHBisola Hamzat

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Overview

Repeated cross-sectional study shows rising opioid agonist treatment in First Nation Peoples, indicating improving access over time.

Key Points

  • This study aims to describe trends in opioid agonist therapy use among First Nation Peoples in Ontario between 2013 and 2023.
  • Population-based repeated cross-sectional study of registered First Nation Peoples aged 15+ in Ontario
  • Reported quarterly proportions of First Nation Peoples dispensed OAT, including methadone, buprenorphine/naloxone, and BUP-ER
  • Examined annual prevalence of OAT dispensing stratified by age, sex, and residence in 2023.
  • Between 2013 and 2023, quarterly OAT dispensing rose from 2.7% to 5.0%, plateauing at about 5% in early 2020.
  • Methadone dispensing remained steady at 2.0% to 2.6%, with buprenorphine-containing products overtaking methadone in mid-2018, reaching 3.1% by Q4 2023.
  • In 2023, 6.1% of First Nation Peoples accessed OAT, with higher rates among those aged 25–44 and residing in First Nation communities.

Cite This Study

Rebić et al. (2026) studied this question.

synapsesocial.com/papers/6a226835763171746d546b9dhttps://doi.org/10.1097/adm.0000000000001726
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