21.8 A 16-ch patient-specific seizure onset and termination detection SoC with machine-learning and voltage-mode transcranial stimulation

Multichannel EEG seizure detection SoCs are widely used in medical practice and in research [1]-[3]. Due to huge variation in seizure patterns, patient-specific seizure detection is very crucial. [1], [2] presents 8-channel (ch) SoCs with moderate latency (~2s) but without seizure termination detection and stimulation. [3] implements a closed-loop SoC but is not patient-specific, and moreover, is invasive. This paper presents an ultra-low power 16-ch "non-invasive, patient-specific" seizure onset and termination detection SoC with channels multiplexing AFE and pulsating voltage transcranial electrical stimulation (PVTES).