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Study Objectives: Patients with obstructive sleep apnea syndrome (OSAS) using continuous positive airway pressure (CPAP) often report pressure-related discomfort. Both lower pressure and increased comfort may improve patients' compliance with CPAPtherapy, thereby improving therapeutic effectiveness. Combining CPAP with an oral appliance (hybrid therapy) could be an adequate alternative therapy.
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Vries et al. (2016) studied this question.
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