Key result
Higher plasma HDL-C levels were associated with decreased mortality in patients with pulmonary arterial hypertension (HR for every 5-mg/dl increase 0.643; 95% CI 0.504-0.822; P=0.001).
Why the study?
Are plasma HDL-C levels associated with mortality and clinical worsening in patients with pulmonary arterial hypertension?
Cohort (n=298)
Are plasma HDL-C levels associated with mortality and clinical worsening in patients with pulmonary arterial hypertension?
Hazard Ratio: 0.643 (95% CI 0.504–0.822)
p-value: p=0.001
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Low plasma HDL-C is an independent predictor of higher mortality and clinical worsening in patients with pulmonary arterial hypertension.
Heresi et al. (2010) conducted a cohort in Pulmonary Arterial Hypertension (n=298). High-density lipoprotein cholesterol (HDL-C) vs. Lower HDL-C levels was evaluated on All-cause mortality (HR 0.643, 95% CI 0.504-0.822, p=0.001). Higher plasma HDL-C levels were associated with decreased mortality in patients with pulmonary arterial hypertension (HR for every 5-mg/dl increase 0.643; 95% CI 0.504-0.822; P=0.001).
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