Why the study?
Do renal injury-related biomarkers predict the development and outcomes of acute cardiorenal syndrome?
Do renal injury-related biomarkers predict the development and outcomes of acute cardiorenal syndrome?
Renal injury-related biomarkers show promise in improving risk stratification and early identification of acute kidney injury in acute cardiorenal syndrome.
Answers are grounded in this paper and cite their sources.
May aid early identification in acute cardiorenal syndrome; hypothesis-generating and requires prospective validation.
BACKGROUND: Acute cardiorenal syndrome (CRS) is a common clinical condition associated with adverse outcomes. Early identification of acute kidney injury in this setting remains challenging given that serum creatinine level is a marker of renal function and not kidney injury. SUMMARY: Several renal injury-related molecules are now available, which may help elucidate the complexities of the organ crosstalk, enabling more accurate risk stratification and effective interventions. KEY MESSAGES: This review highlights the major studies that have characterized the diagnostic and prognostic predictive power of these biomarkers with reference to acute CRS. Although more research is needed, the current results are very promising.
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Hou et al. (2016) studied this question.
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