Seventy‐five apparently healthy 16–17 year old schoolboys have been studied for the presence of pre‐β‐1 lipoprotein by two separate methods of lipoprotein electrophoresis. Forty‐three per cent of the boys revealed a detectable pre‐β‐1 lipoprotein. The pre‐β‐1 positive group had a higher mean value of total ( p < 0.01) and free ( p <0.01) cholesterol than the pre‐β‐1 negative group. A higher mean value of total CO 2 ( p <0.02) and a lower chloride value ( p <0.05) were also found in the pre‐β‐1 positive group. Six young males with the most prominent pre‐β‐1 lipoprotein fraction also showed a higher value of hematocrit ( p < 0.05). These results may provide further explanation for the higher incidence of CHD previously found among pre‐β‐1 positive middle‐aged males.
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Dahlén et al. (1974) studied this question.
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