Key result
Higher monocyte to high-density lipoprotein ratio on postoperative day 1, aging, larger left atrial diameter, IABP use, and greater blood transfusion were independent risk factors for new-onset AF.
Why the study?
Postoperative atrial fibrillation is a common complication of coronary revascularization with unclear mechanisms, prompting investigation into risk factors and the early warning value of clinical inflammatory markers.
What are the independent risk factors for new-onset atrial fibrillation after coronary revascularization?
Cohort (n=293)
No
What are the independent risk factors for new-onset atrial fibrillation after coronary revascularization?
Elevated monocyte to high-density lipoprotein ratio on postoperative day 1, along with aging and other clinical factors, is an independent risk factor for new-onset atrial fibrillation after coronary revascularization.
Higher monocyte-HDL ratio may aid postoperative AF risk stratification after revascularization; hypothesis-generating and should not yet change practice.
Atrial fibrillation (AF) is a common complication of coronary revascularization. Currently, the mechanisms of postoperative AF are unclear. This study was aimed at investigating the risk factors for new-onset AF (NOAF) after coronary revascularization and exploring the early warning effects of clinical inflammatory markers. A retrospective analysis was conducted on 293 patients with unstable angina pectoris who underwent coronary artery revascularization in Beijing Chao-Yang Hospital, Capital Medical University, between April 2018 and June 2021, including 224 patients who underwent coronary artery bypass grafting and 69 patients who underwent one-step hybrid coronary revascularization. Baseline data, clinical data, blood indicators and AF episodes within 7 days after the surgery were collected. Participants were divided into two groups according to whether AF occurred, and the data were analyzed between groups. In addition, multivariate logistic regression was used to explore the independent risk factors for developing AF post coronary revascularization. Aging, a larger left atrial inferior-superior diameter, use of an intra-aortic balloon pump, a greater blood volume transfused during perioperative period and a higher monocyte to high-density lipoprotein ratios on postoperative day 1 were independent risk factors for NOAF after coronary artery surgery.
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Mu et al. (2023) conducted a cohort in Unstable angina pectoris (n=293). Elevated monocyte to high-density lipoprotein ratio was evaluated on New-onset atrial fibrillation (NOAF) within 7 days after surgery. Higher monocyte to high-density lipoprotein ratio on postoperative day 1, aging, larger left atrial diameter, IABP use, and greater blood transfusion were independent risk factors for new-onset AF.
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