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February 27, 2018Frontiers in ImmunologyOpen Access

Valproic Acid Combined with Zoledronate Enhance γδ T Cell-Mediated Cytotoxicity against Osteosarcoma Cells via the Accumulation of Mevalonate Pathway Intermediates

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Authors

SWShengdong WangHLHengyuan LiCYChenyi Ye

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Wang et al. (2018) studied this question.

synapsesocial.com/papers/6a22aea2e4d98b33c2d2ca99https://doi.org/10.3389/fimmu.2018.00377
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Interleukin-12 and interleukin-18 change ICAM-I expression, and enhance natural killer cell mediated cytolysis of human osteosarcoma cells2002 · 20 citations
  2. 2γδ Cells: A Right Time and a Right Place for a Conserved Third Way of Protection2000 · 1,139 citations
  3. 3T-Cell-Based Immunotherapy for Osteosarcoma: Challenges and Opportunities2016 · 75 citations
  4. 4Human T Cell Receptor γδ Cells Recognize Endogenous Mevalonate Metabolites in Tumor Cells2003 · 849 citations