Answers are grounded in this paper and cite their sources.
methods to elucidate the reasons associated with the resistance of clinically relevant RASs. Dasabuvir was docked at the palm-I site and was found to form hydrogen bonds with the residues S288, I447, Y448, N291 and D318. The RAS positions 316, 414, 448, 553 and 556 were found to constitute the dasabuvir binding pocket.
No takes yet. Share an insight, caveat, or question.
Akaberi et al. (2018) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: