Lyt 1 cells respond to la‐bearing macrophages in the murine syngeneic mixed lymphocyte reaction

An autologous mixed lymphocyte reaction has been described in mice and humans in which T cells proliferate following stimulation with syngeneic non-T cells. This report demonstrates that in the murine syngeneic mixed lymphocyte reaction, the responder cell is an Ly1+, Ly23-, Qa-1-T cell. The stimulator is an Ia-bearing macrophage-like cell.