Key result
Typical symptoms were more predictive of acute coronary syndromes in younger patients (<70 years) than older patients, with a 36% greater odds per additional symptom (OR 1.36; 95% CI 1.02-1.83).
Why the study?
Do typical symptoms predict acute coronary syndromes differently in younger (< 70 years) versus older (>= 70 years) patients?
Population
531 patients presenting to the emergency department of a regional cardiac referral center in New England…
Design
Cohort
Authors
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May support higher ACS suspicion in older adults despite atypical symptoms; hypothesis-generating and requires prospective validation.
Observational (n=531)
No
Do typical symptoms predict acute coronary syndromes differently in younger (< 70 years) versus older (>= 70 years) patients?
Odds Ratio: 1.36 (95% CI 1.02–1.83)
p-value: p=0.038
Typical symptoms of ACS are predictive of the diagnosis in younger patients (<70 years) but are less predictive in older patients (>=70 years), highlighting the need for a higher index of suspicion in the elderly.
Milner et al. (2001) conducted an observational in Acute Coronary Syndromes (n=531). Typical symptoms vs. Older age (≥70 years) or fewer symptoms was evaluated on Diagnosis of Acute Coronary Syndromes (ACS) (OR 1.36, 95% CI 1.02-1.83, p=0.038). Typical symptoms were more predictive of acute coronary syndromes in younger patients (<70 years) than older patients, with a 36% greater odds per additional symptom (OR 1.36; 95% CI 1.02-1.83).
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