Key result
In 14 patients with floppy mitral valve syndrome requiring surgery, the clinical course was typified by rapidly progressive disability, with abrupt deterioration in 5 patients.
Observational (n=14)
Floppy mitral valve syndrome can present with rapidly progressive disability and atypical physical findings, such as the absence of mid-systolic clicks due to anterior cusp redundancy.
Alerts to rapid deterioration risk in floppy mitral valve; small case series leaves natural history and predictors open.
The correlation of clinical features with the operative findings in 14 patients with a floppy mitral valve is discussed. The clinical course is typified by rapidly progressive disability. An abrupt deterioration was present in five of our subjects and this may be due to rupture of chordae tendinea or stretching of the valve apparatus. The redundancy of the anterior cusp in 13 of our series may explain the absence of mid systolic clicks in all except one patient. The diagnosis of prolapse can be difficult to make prior to surgery because the prolapsed cusp may be masked by the regurgitant contrast medium. Hypokinesis and prominent inflow sacculation of the left ventricular inflow tract suggest an associated myocardial abnormality. Calcium was present in one valve and thus mitral valve calcification does not exclude the possibility of a floppy valve in patients with mitral regurgitation.
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Luxton et al. (1975) conducted an observational in Floppy mitral valve syndrome (n=14). Floppy mitral valve syndrome was evaluated on Clinical features and operative findings. In 14 patients with floppy mitral valve syndrome requiring surgery, the clinical course was typified by rapidly progressive disability, with abrupt deterioration in 5 patients.
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