Simultaneous renal clearances of 125I-iothalamate and inulin were performed in ten patients. The mean 125Iiothalamate-to-inulin clearance ratio was 1·018. In two patients, the clearance of 131I-iothalamate was found to be similar to that of the 131I form which is known to be excreted by glomerular filtration only. 125I-iothalamate provides an accurate measurement of glomerular nitration rate in man.
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Elwood et al. (1967) studied this question.
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