Key result
Resistance exercise lowers acute post-exercise systolic BP by ~6 mmHg without sustaining 24-hour ambulatory reductions in PAD.
Why the study?
Does a single bout of resistance exercise reduce blood pressure and cardiac work in patients with peripheral artery disease?
RCT (n=17)
Single-blind (patients blinded until intervention, observer blinded)
Randomized cross-over
Does a single bout of resistance exercise reduce blood pressure and cardiac work in patients with peripheral artery disease?
A single session of resistance exercise provides acute but transient reductions in blood pressure and cardiac work, without long-term ambulatory hypotensive effects in patients with peripheral artery disease.
Single resistance exercise sessions yield only transient BP effects in PAD; extends acute response data while leaving 24-hour ambulatory benefits open.
OBJECTIVE: To analyze the posteffects of a single bout of resistance exercise on cardiovascular parameters in patients with peripheral artery disease (PAD). DESIGN: Randomized cross-over. MATERIALS AND METHODS: Seventeen PAD patients performed two experimental sessions: control (C) and resistance exercise (R). Both sessions were identical (eight exercises, 3×10 repetitions), except that the R session was performed with an intensity between 5 and 7 in the OMNI-RES scale and the C session was performed without any load. Systolic blood pressure (BP), diastolic BP, heart rate, and rate-pressure product (RPP) were measured for 1 h after the interventions in the laboratory and during 24-h using ambulatory BP monitoring. RESULTS: After the R session, systolic BP (greatest reduction: -6±2 mmHg, P<0.01) and RPP (greatest reduction: -888±286 mmHg×bpm; P<0.01) decreased until 50 min after exercise. From the second hour until 23 h after exercise, BP, heart rate, and RPP product were similar (P>0.05) between R and C sessions. BP load, nocturnal BP fall, and morning surge were also similar between R and C sessions (P>0.05). CONCLUSION: A single bout of resistance exercise decreased BP and cardiac work for 1 h after exercise under clinical conditions, and did not modify ambulatory cardiovascular variables during 24 h in patients with PAD.
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Rodrigues et al. (2014) conducted an RCT in Peripheral artery disease (PAD) (n=17). Resistance exercise vs. Control session (identical 8 exercises without any load) was evaluated on Systolic blood pressure reduction up to 50 min post-exercise (-6±2 mmHg, p=<0.01). A single bout of resistance exercise reduced systolic blood pressure by up to 6 mmHg for 1 hour post-exercise, but did not modify ambulatory cardiovascular variables over 24 hours in PAD patients.
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