Population
Anesthetized mongrel dogs
Comparison
Bilateral supramaximal phrenic nerve stimulation… vs Different contraction frequencies and duty cycles
Design
Preclinical
Authors
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May inform duty cycle selection in animal ventilation models; leaves open translation to human diaphragmatic perfusion.
Frequency of contraction is a major determinant of diaphragmatic blood flow, and high duty cycle impedes it.
Buchler et al. (1985) studied this question.