Characterization of human high density lipoproteins by zonal ultracentrifugation.

The abbreviations used are: HDL, high density lipoproteins; HDL, high density lipoproteins2; HDLs, high density lipoproteinss; VLDL, very low density lipoproteins; LDL, low density lipoproteins; SDS-PAGE, polyacrylamide gel electrophoresis in 0.1% sodium dodecyl sulfate; apo-A-I (Mr = 28,331) and apo-A-I1 (M, = 17,380), principal apoprotein constituents of HDL; apo-C-I1 (M, = 8,300) and apo-C-111 (M, = 8,764).major and minor apoprotein constituents of 'Since the subfraction bands displayed good symmetry, we assumed that the peak sufficiently approximated the center of mass, i.e. the parameter recommended by Schumaker (23).