The authors examined the effects of certain nonpsychiatric variables on dexamethasone suppression test (DST) results. Sixty physically healthy, nondepressed, nondemented adults participated in a standard outpatient 1-mg DST. Postdexamethasone plasma cortisol concentrations were higher in older subjects and were lower in more obese subjects. The authors conclude that age and relative weight influence cortisol suppression in healthy subjects.
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Weiner et al. (1987) studied this question.
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