What question did this study set out to answer?

The aim is to investigate how ATP analogs affect the low-angle X-ray diffraction pattern of insect flight muscle.

January 1, 1973Cold Spring Harbor Symposia on Quantitative Biology

Effects of ATP Analogs on the Low-Angle X-Ray Diffraction Pattern of Insect Flight Muscle

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Authors

JLJ. Barrington LeighUniversity of Alberta KHKenneth C. HolmesMassachusetts Eye and Ear Infirmary HMHans Georg MannherzSt. Josef-Hospital

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Implication

ATP effects on insect muscle diffraction remain hypothesis-generating; leaves open translation to cardiac cross-bridge function pending mammalian studies.

Key Points

The aim is to investigate how ATP analogs affect the low-angle X-ray diffraction pattern of insect flight muscle.
Evaluated changes in low-angle X-ray diffraction patterns of glycerinated insect flight muscle fibers.
Utilized electron microscopy to observe alterations in cross-bridge orientation.
ATP presence induced a strong meridional reflection at 145 Å spacing.
With ATP removal, the reflection shifted to a 380 Å layer line.
Cross-bridges transitioned from a 45° orientation in the absence of ATP to a right angle under ATP influence.

Cite This Study

Leigh et al. (1973) studied this question.

synapsesocial.com/papers/6a22fddbc650520b07cb1fd3 https://doi.org/10.1101/sqb.1973.037.01.055

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Implication

ATP effects on insect muscle diffraction remain hypothesis-generating; leaves open translation to cardiac cross-bridge function pending mammalian studies.

Effects of ATP Analogs on the Low-Angle X-Ray Diffraction Pattern of Insect Flight Muscle

Discussion

Member takes

Implication

Key Points

Cite This Study

Effects of ATP Analogs on the Low-Angle X-Ray Diffraction Pattern of Insect Flight Muscle

Discussion

Member takes

Implication

Key Points

Cite This Study

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